| Item Type | Name |
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Concept
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Glycogen Synthase Kinase 3 beta
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Concept
|
Theranostic Nanomedicine
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Concept
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Adenovirus Infections, Human
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Concept
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Age Factors
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Concept
|
Antibodies
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Concept
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Antibodies, Monoclonal
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Concept
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Antibodies, Neoplasm
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Concept
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Mechanistic Target of Rapamycin Complex 1
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Concept
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Mechanistic Target of Rapamycin Complex 2
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Concept
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Acetylation
|
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Concept
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Amino Acid Sequence
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Concept
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Acylation
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Concept
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Adenocarcinoma
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Concept
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Carbon Isotopes
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Concept
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Carcinoma
|
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Concept
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Carcinoma in Situ
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Concept
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Cyclic AMP
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Concept
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Base Sequence
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Concept
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Cytoplasm
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Concept
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Cytoskeleton
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Concept
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Chromatography, Affinity
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Concept
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Diabetes Mellitus, Experimental
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Concept
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Diabetes Mellitus, Type 1
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Concept
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Diabetes Mellitus, Type 2
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Concept
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Eukaryotic Cells
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Concept
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Cysteine
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Concept
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Colonic Neoplasms
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Concept
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Endocytosis
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Concept
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Endoplasmic Reticulum
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Concept
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Epithelial Cells
|
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Concept
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Escherichia coli
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Concept
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Estradiol
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Concept
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Estrogens
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Concept
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Cyclic GMP
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Concept
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Guanylate Cyclase
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Concept
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Electrophoresis, Polyacrylamide Gel
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|
Concept
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Electroretinography
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Concept
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Humans
|
|
Concept
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Genes, Synthetic
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Concept
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Hydrogen Peroxide
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Concept
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Glial Fibrillary Acidic Protein
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Concept
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Liposomes
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Concept
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Glucose
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Concept
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Glycolysis
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Concept
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Glycoproteins
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Concept
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Macular Degeneration
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Concept
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Insulin
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Concept
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Insulin-Like Growth Factor I
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Concept
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Introns
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Inbred C57BL
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Concept
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Actin Cytoskeleton
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Concept
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Microscopy, Fluorescence
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|
Concept
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Polyethylene Glycols
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|
Concept
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Mitochondria
|
|
Concept
|
Phosphatidylcholines
|
|
Concept
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Phosphatidylethanolamines
|
|
Concept
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Phosphatidylinositols
|
|
Concept
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Molecular Sequence Data
|
|
Concept
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Molecular Weight
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|
Concept
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Precipitin Tests
|
|
Concept
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Sensitivity and Specificity
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|
Concept
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Ribosomes
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|
Concept
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RNA
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Concept
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RNA, Messenger
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Concept
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Tamoxifen
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Concept
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Radiation Injuries, Experimental
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|
Concept
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Rats, Inbred Strains
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Concept
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Receptors, Cell Surface
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Concept
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Receptor, Insulin
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Concept
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3',5'-Cyclic-AMP Phosphodiesterases
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Concept
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Ion Channel Gating
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Concept
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Blotting, Southern
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|
Concept
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Immunoblotting
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|
Concept
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Blotting, Northern
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Concept
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Blotting, Western
|
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Concept
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Oncogene Protein pp60(v-src)
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|
Concept
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Colorectal Neoplasms
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|
Concept
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Drug Design
|
|
Concept
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Transducin
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|
Concept
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Genetic Therapy
|
|
Concept
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Vimentin
|
|
Concept
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Receptor, IGF Type 1
|
|
Concept
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Vision, Ocular
|
|
Concept
|
Mutagenesis, Site-Directed
|
|
Concept
|
ras Proteins
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|
Concept
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Neuroprotective Agents
|
|
Concept
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Evolution, Molecular
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|
Concept
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GTP-Binding Proteins
|
|
Concept
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Receptor Cross-Talk
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|
Concept
|
I-kappa B Proteins
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|
Concept
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rab5 GTP-Binding Proteins
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|
Concept
|
DNA, Complementary
|
|
Concept
|
Phosphatidylinositol Phosphates
|
|
Concept
|
Receptor Protein-Tyrosine Kinases
|
|
Concept
|
Mice, Knockout
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|
Concept
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Calcineurin
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Concept
|
1-Phosphatidylinositol 4-Kinase
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|
Concept
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Databases as Topic
|
|
Concept
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Progesterone
|
|
Concept
|
Receptors, G-Protein-Coupled
|
|
Concept
|
Ubiquitin-Protein Ligases
|
|
Concept
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Proto-Oncogene Proteins c-akt
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|
Concept
|
Frizzled Receptors
|
|
Concept
|
GRB7 Adaptor Protein
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|
Concept
|
GRB10 Adaptor Protein
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|
Concept
|
Hippocalcin
|
|
Concept
|
Recoverin
|
|
Concept
|
Guanylate Cyclase-Activating Proteins
|
|
Concept
|
Cyclic Nucleotide-Gated Cation Channels
|
|
Concept
|
Opsins
|
|
Concept
|
Insulin Receptor Substrate Proteins
|
|
Concept
|
Light Signal Transduction
|
|
Concept
|
Survival Rate
|
|
Concept
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Case-Control Studies
|
|
Concept
|
MicroRNAs
|
|
Concept
|
Genes, p53
|
|
Concept
|
Interleukin-8
|
|
Concept
|
beta-Cyclodextrins
|
|
Concept
|
Immunoprecipitation
|
|
Concept
|
ErbB Receptors
|
|
Concept
|
p38 Mitogen-Activated Protein Kinases
|
|
Concept
|
In Vitro Techniques
|
|
Concept
|
Glycogen Synthase Kinase 3
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
DNA Primers
|
|
Concept
|
Phosphatidylinositol 4,5-Diphosphate
|
|
Concept
|
Lactic Acid
|
|
Concept
|
Hedgehog Proteins
|
|
Concept
|
Arrestin
|
|
Concept
|
Injections, Intraocular
|
|
Concept
|
HEK293 Cells
|
|
Concept
|
MAP Kinase Signaling System
|
|
Concept
|
Transport Vesicles
|
|
Concept
|
Protein Tyrosine Phosphatases, Non-Receptor
|
|
Concept
|
Protein Tyrosine Phosphatase, Non-Receptor Type 1
|
|
Concept
|
Cyclic Nucleotide Phosphodiesterases, Type 1
|
|
Concept
|
Cyclic Nucleotide Phosphodiesterases, Type 6
|
|
Concept
|
Intravitreal Injections
|
|
Concept
|
Class I Phosphatidylinositol 3-Kinases
|
|
Concept
|
Class Ia Phosphatidylinositol 3-Kinase
|
|
Concept
|
Class Ib Phosphatidylinositol 3-Kinase
|
|
Concept
|
TOR Serine-Threonine Kinases
|
|
Concept
|
Caspase 3
|
|
Concept
|
DNA
|
|
Concept
|
Gallbladder Neoplasms
|
|
Concept
|
Hypoglycemic Agents
|
|
Concept
|
Immunoenzyme Techniques
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Organ Culture Techniques
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|
Academic Article
|
Insulin receptor signaling in cones.
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|
Academic Article
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Corneal cell survival in adenovirus type 19 infection requires phosphoinositide 3-kinase/Akt activation.
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Academic Article
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Light regulation of the insulin receptor in the retina.
|
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Academic Article
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Molecular characterization of a gene encoding N-myristoyl transferase (NMT) from Triticum aestivum (bread wheat).
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|
Academic Article
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Activation and membrane binding of retinal protein kinase Balpha/Akt1 is regulated through light-dependent generation of phosphoinositides.
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|
Academic Article
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Rhodopsin-regulated insulin receptor signaling pathway in rod photoreceptor neurons.
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Academic Article
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The p110a isoform of phosphoinositide 3-kinase is essential for cone photoreceptor survival.
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|
Academic Article
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MicroRNA-184 modulates canonical Wnt signaling through the regulation of frizzled-7 expression in the retina with ischemia-induced neovascularization.
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Academic Article
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Involvement of insulin/phosphoinositide 3-kinase/Akt signal pathway in 17 beta-estradiol-mediated neuroprotection.
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Academic Article
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Diabetes reduces autophosphorylation of retinal insulin receptor and increases protein-tyrosine phosphatase-1B activity.
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|
Academic Article
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Growth factor receptor-bound protein 14 undergoes light-dependent intracellular translocation in rod photoreceptors: functional role in retinal insulin receptor activation.
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Academic Article
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Cytoskeletal components enhance the autophosphorylation of retinal insulin receptor.
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Academic Article
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Enhanced retinal insulin receptor-activated neuroprotective survival signal in mice lacking the protein-tyrosine phosphatase-1B gene.
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Academic Article
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Impaired association of retinal degeneration-3 with guanylate cyclase-1 and guanylate cyclase-activating protein-1 leads to leber congenital amaurosis-1.
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Academic Article
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Photoreceptor Neuroprotection: Regulation of Akt Activation Through Serine/Threonine Phosphatases, PHLPP and PHLPPL.
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Academic Article
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In vivo regulation of phosphoinositide 3-kinase in retina through light-induced tyrosine phosphorylation of the insulin receptor beta-subunit.
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Academic Article
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Identification of a NPXY motif in growth factor receptor-bound protein 14 (Grb14) and its interaction with the phosphotyrosine-binding (PTB) domain of IRS-1.
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Academic Article
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Lipid-protein interactions of growth factor receptor-bound protein 14 in insulin receptor signaling.
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Academic Article
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Localization of the insulin receptor and phosphoinositide 3-kinase in detergent-resistant membrane rafts of rod photoreceptor outer segments.
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Academic Article
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G-protein-coupled receptor rhodopsin regulates the phosphorylation of retinal insulin receptor.
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Academic Article
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Loss of neuroprotective survival signal in mice lacking insulin receptor gene in rod photoreceptor cells.
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Academic Article
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Insulin growth factor 1 receptor/PI3K/AKT survival pathway in outer segment membranes of rod photoreceptors.
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Academic Article
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Insulin receptor signaling regulates actin cytoskeletal organization in developing photoreceptors.
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Academic Article
|
Phosphoinositide 3-kinase signaling in the vertebrate retina.
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|
Academic Article
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Serine/threonine kinase akt activation regulates the activity of retinal serine/threonine phosphatases, PHLPP and PHLPPL.
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Academic Article
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Light-induced tyrosine phosphorylation of rod outer segment membrane proteins regulate the translocation, membrane binding and activation of type II a phosphatidylinositol-5-phosphate 4-kinase.
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Academic Article
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Neuroprotective role of protein tyrosine phosphatase-1B in rod photoreceptor neurons.
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Academic Article
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Effect of knocking down the insulin receptor on mouse rod responses.
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Academic Article
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Activation of oncogenic tyrosine kinase signaling promotes insulin receptor-mediated cone photoreceptor survival.
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Academic Article
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Interaction of the insulin receptor beta-subunit with phosphatidylinositol 3-kinase in bovine ROS.
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Academic Article
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Interaction of the retinal insulin receptor beta-subunit with the p85 subunit of phosphoinositide 3-kinase.
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Academic Article
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Regulation of retinal phosphoinositide 3-kinase activity in p85alpha-subunit knockout mice.
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Academic Article
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Neuroprotective effect of estrogen upon retinal neurons in vitro.
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Academic Article
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Retinal insulin receptor signaling in hyperosmotic stress.
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Academic Article
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Growth factor receptor-bound protein 14: a new modulator of photoreceptor-specific cyclic-nucleotide-gated channel.
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|
Academic Article
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Phosphorylated Grb14 is an endogenous inhibitor of retinal protein tyrosine phosphatase 1B, and light-dependent activation of Src phosphorylates Grb14.
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Academic Article
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Protein tyrosine phosphatase 1B: a novel molecular target for retinal degenerative diseases.
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Academic Article
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Insulin receptor regulates photoreceptor CNG channel activity.
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Academic Article
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Light activation of the insulin receptor regulates mitochondrial hexokinase. A possible mechanism of retinal neuroprotection.
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Academic Article
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Spatial and temporal aspects and the interplay of Grb14 and protein tyrosine phosphatase-1B on the insulin receptor phosphorylation.
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|
Academic Article
|
Constitutive Activation Mutant mTOR Promote Cone Survival in Retinitis Pigmentosa Mice.
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Academic Article
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A non-canonical rhodopsin-mediated insulin receptor signaling pathway in retinal photoreceptor neurons.
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|
Grant
|
Light Activation of Retinal Insulin Receptor Signaling
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|
Grant
|
Mechanistic studies on obesity-deteriorated glucose and lipid metabolisms
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|
Academic Article
|
Regulation of Phosphoinositide Levels in the Retina by Protein Tyrosine Phosphatase 1B and Growth Factor Receptor-Bound Protein 14.
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|
Academic Article
|
ßA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells.
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Academic Article
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Ribosomal targeting strategy and nuclear labeling to analyze photoreceptor phosphoinositide signatures.
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Academic Article
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Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection.
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Academic Article
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Study of B72.3 combining sites by molecular modeling and site-directed mutagenesis.
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